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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASPM
All Species:
10
Human Site:
S446
Identified Species:
31.43
UniProt:
Q8IZT6
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZT6
NP_060606.3
3477
409800
S446
P
E
C
Q
G
S
K
S
P
K
A
I
F
E
E
Chimpanzee
Pan troglodytes
P62293
3477
409724
S446
P
E
C
Q
G
S
K
S
P
K
A
I
F
E
E
Rhesus Macaque
Macaca mulatta
P62292
3479
410087
S446
P
E
Y
Q
G
S
K
S
P
K
A
I
F
E
E
Dog
Lupus familis
XP_537130
3407
401187
R422
S
Q
D
K
L
T
R
R
P
I
L
S
A
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CJ27
3122
364103
T345
T
V
H
E
V
C
Q
T
I
L
S
P
D
S
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506218
2691
320176
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116845
3391
394231
V431
P
V
N
S
A
T
V
V
K
S
K
A
D
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787918
3597
412342
E503
P
G
H
E
D
V
R
E
E
L
V
I
E
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.8
79.1
N.A.
63.2
N.A.
N.A.
50.1
N.A.
N.A.
39
N.A.
N.A.
N.A.
N.A.
31.4
Protein Similarity:
100
99.4
97.9
87.8
N.A.
74.8
N.A.
N.A.
63.5
N.A.
N.A.
59.9
N.A.
N.A.
N.A.
N.A.
53
P-Site Identity:
100
100
93.3
6.6
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
33.3
N.A.
26.6
N.A.
N.A.
0
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
0
0
0
38
13
13
13
0
% A
% Cys:
0
0
25
0
0
13
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
13
0
0
0
0
0
0
0
25
0
0
% D
% Glu:
0
38
0
25
0
0
0
13
13
0
0
0
13
50
38
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
38
0
13
% F
% Gly:
0
13
0
0
38
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
13
0
50
0
0
13
% I
% Lys:
0
0
0
13
0
0
38
0
13
38
13
0
0
0
0
% K
% Leu:
0
0
0
0
13
0
0
0
0
25
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
63
0
0
0
0
0
0
0
50
0
0
13
0
0
0
% P
% Gln:
0
13
0
38
0
0
13
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
25
13
0
0
0
0
0
0
0
% R
% Ser:
13
0
0
13
0
38
0
38
0
13
13
13
0
13
13
% S
% Thr:
13
0
0
0
0
25
0
13
0
0
0
0
0
13
13
% T
% Val:
0
25
0
0
13
13
13
13
0
0
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _